Cosmetics (colloquially known as makeup or make-up) are care substances used to enhance the appearance or odor of the human body. They are generally mixtures of chemical compounds, some being derived from natural sources, many being synthetic.[1] In the U.S., the Food and Drug Administration (FDA) which regulates cosmetics,[2] defines cosmetics as "intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions." This broad definition includes, as well, any material intended for use as a component of a cosmetic product. The FDA specifically excludes soap from this category. Human physical appearance refers to the outward phenotype or look of human beings. There are infinite variations in human phenotypes, though society reduces the variability to distinct categories. Physical appearance of humans, in particular those attributed which are regarded as important for physical attractiveness, are believed by anthropologists to significantly affect the development of personality and social relations. Humans are acutely sensitive to their physical appearance, some theorize for reasons of evolution. Some differences in human appearance are genetic, others are the result of age, lifestyle or disease, and many are the result of personal adornment. Some people have traditionally linked some differences in personal appearance such as skeletal shape with ethnicity, such as prognathism or elongated stride. Different cultures place different degrees of emphasis on physical appearance and its i

portance to social status and other phenomena. The Food and Drug Administration (FDA or USFDA) is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments. The FDA is responsible for protecting and promoting public health through the regulation and supervision of food safety, tobacco products, dietary supplements, prescription and over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), and veterinary products. The FDA also enforces other laws, notably Section 361 of the Public Health Service Act and associated regulations, many of which are not directly related to food or drugs. These include sanitation requirements on interstate travel and control of disease on products ranging from certain household pets to sperm donation for assisted reproduction. The FDA is led by the Commissioner of Food and Drugs, appointed by the President with the advice and consent of the Senate. The Commissioner reports to the Secretary of Health and Human Services. The 21st and current Commissioner is Dr. Margaret A. Hamburg. She has served as Commissioner since February 2009. The FDA has its headquarters in unincoporated White Oak, Maryland.[4] The agency also has 223 field offices and 13 laboratories located throughout the 50 states, the United States Virgin Islands, and Puerto Rico.[2] In 2008, the FDA started opening offices in foreign countries, including China, India, Costa Rica, Chile, Belgium, and the United Kingdom.[5]